Fructose-sweetened drinks may increase risk for cardiovascular disease

Source of Article:

2/17/2009-A study conducted by researchers at the Monell Chemical Senses Center shows obese people who drink fructose-sweetened beverages with their meals may have increased levels of triglycerides following the meal. Triglycerides are manufactured by the body from dietary fat and are the most common form of fat transported in blood. Although normal levels of triglycerides are essential for good health, high levels are associated with increased risk for atherosclerosis and other predictors of cardiovascular disease.

For the study, the researchers had 17 obese men and women admitted twice to the Clinical and Translational Research Center at the Univ. of Pennsylvania. On each admission, the subjects were given identical meals and blood was collected from an intravenous catheter over a 24-hr period. The only difference was the sweetener used in the beverages that accompanies the meals; they were sweetened with glucose during one admission and with fructose during the other. The researchers found that blood triglyceride levels were almost 200% higher when the subjects drank fructose-sweetened beverages than when they drank glucose-sweetened beverages. In addition, this effect was especially pronounced in insulin-resistant subjects, who already had increased triglyceride levels.

The study was published in the Journal of Clinical Endocrinology and Metabolism.


Monell release



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