July 21, 2009, 11:05
TCD researchers find salmonella gene
of Article: http://www.irishtimes.com/newspaper/breaking/2009/0721/breaking26.htm
Scientists at Trinity
College Dublin have made a discovery which could help to develop new ways
to kill the salmonella bacteria.
Salmonella causes food
poisoning and kills around one million people around the world every year.
This discovery of the
salmonella control gene could eventually reduce disease levels which are
caused by salmonella.
The bug can survive very
harsh conditions in the body which kill most germs. It does this by
switching genes on and off quickly and adding outer membrane proteins to cope
with the new environment. The outer membrane proteins allows salmonella to
survive in salty environments and to kill people.
The research has
uncovered a new mechanism used by salmonella to control outer membrane
“We hope that in the
future scientists will be able to use the findings to develop new ways to
kill salmonella. It is an exciting step on the path of reducing the levels
of salmonella and reducing human disease worldwide,” said Professor Jay
Hinton, Stokes Professor of Microbial Pathogenesis, Trinity College Dublin.
The research by
scientists from Trinity College Dublin, the Institute of Food Research in
the UK and the Max Planck Institute for Infection Biology has just been
published in the journal Nature Structural and Molecular Biology.