in the Treatment and Diagnosis of Food Allergy: Presented at the 2004 AAAAI Annual
March 22, 2004
From a press release
-- The major peanut allergen, Ara h 1, does not appear to be widely distributed
in schools, according to a study presented at the American Academy of Allergy,
Asthma and Immunology's (AAAAI) 2004 Annual Meeting in San Francisco.
T. Perry, MD, and colleagues from Johns Hopkins School of Medicine examined several
factors: peanut allergen on surfaces in schools, the presence of residual peanut
protein after using cleaning products, and airborne peanut protein when people
were eating several forms of peanut.
After cleaning hands with liquid soap,
bar soap or commercial wipes, the peanut allergen was undetectable. However, plain
water and antibacterial hand sanitizer left detectable peanut allergen on 3/10
hands. Common household cleaning agents, except dishwashing liquid, easily removed
peanut allergen from tabletops.
Despite fear of airborne peanut allergens,
the study was unable to detect any after simulating real-life situations when
peanut butter, shelled peanuts and unshelled peanuts were consumed.
to Dietary Proteins released in Breast Milk Causing Colic in Infants
in breast-fed infants younger than 6 weeks of age is associated with intolerance
to dietary proteins excreted in breast milk. These findings were presented today
at the 2004 AAAAI Annual Meeting in San Francisco.
Over a seven-day period,
David J Hill, FAAAAI, and colleagues from Royal Children's Hospital, Melbourne,
Australia, studied breastfed infants with colic less than 6 weeks old. Mothers
were randomly assigned to a "low- allergen" diet that excluded milk,
egg, wheat, peanut, tree nuts and fish or a "control" diet that included
Ninety infants completed the program; 47 receiving the "low
allergen" and 43 the "control" diet. More children in the "low-allergen"
group (74%) than in the control group (34%) saw a 25% decrease in their distress.
In the last 48 hours of the study, the "low-allergen" group had 128
minutes less distress than the "control" group.
The results of this
study suggest that breast fed infants less than 6 weeks of age with colic may
be allergic to trace amounts of dietary protein normally excreted in breast milk.
The researchers found that breastfed infants less than 6 weeks old respond positively
when breastfeeding mothers are placed on a low allergen diet.
self-reported seafood allergy in the United States
diagnosed and/or convincing allergy to seafood is reported by 2.3% of the general
population, or an estimated 6.5 million Americans, according to a study presented
at the 2004 AAAAI Annual Meeting in San Francisco.
Scott Sicherer, MD, FAAAAI,
and colleagues from Mount Sinai School of Medicine surveyed 5,529 households in
a nationwide, cross-sectional, random sample telephone interview using a standardized
questionnaire and predetermined criteria to indicate seafood allergy.
2.8% of adults and 0.6% of children under the age of 18 reported allergy
to some seafood
Multiple reactions were reported by 53% for fish and 57% for
Medical care was sought by 55% with fish and 40% with shellfish
found that the most common offending foods were salmon, tuna and halibut among
fish and shrimp, crab and lobster among shellfish.
Common food allergens found
in pediatric skin care products
Common allergenic foods are widely present
in all types of pediatric skin care products, which may represent a previously
unknown source of exposure, according to a study presented at the 2004 AAAAI Annual
Meeting in San Francisco.
Kelly K.M. Newhall, MD, and colleagues from Children's
Memorial Hospital in Chicago, examined 293 pediatric skin care products (PSCPs).
The PSCPs labels were reviewed and vague ingredients like "fragrances"
and "vegetables" were identified by manufacturers. The common allergenic
foods (CAFs) recorded were cow milk, soy, wheat, egg, peanut, hydrolyzed soy and
Results from the study:
26.6% of the products contained CAFs
and 46% contained other foods
Tree nuts were present in 14% of the products
milk, wheat, soy and hydrolyzed soy were least found
Lotions, creams and baby
oils were most likely to contain CAFs
No products contained egg or peanuts
findings suggest that common pediatric skin care products should be suspected
by parents as a source of exposure for their child's allergic reaction.
Chinese herbal medicine prevents anaphylaxis in peanut-allergic mice
herbal medicine formula completely prevented anaphylaxis in peanut-allergic mice,
according to a study presented at the 2004 AAAAI Annual Meeting in San Francisco.
D. Srivastava, MS, and colleagues of Mount Sinai School of Medicine, gave an oral
treatment of Chinese herbal medicine formula (FAHF-2) to peanut- allergic mice
twice a day for seven weeks. The peanut-specific IgE was considerably reduced
in the FAHF-2 treated mice compared to the control mice in early and later treatments.
The FAHF-2 completely protected the mice from anaphylaxis. The treated mice had
a higher body temperature and significantly lower plasma histamine than the control
These studies were presented at the 2004 Annual Meeting of the American
Academy of Allergy, Asthma and Immunology (AAAAI), taking place March 19-23, 2004
in San Francisco. The AAAAI is the largest professional medical specialty organization
in the United States representing allergists, asthma specialists, clinical immunologists,
allied health professionals and others with a special interest in the research
and treatment of allergic disease. Established in 1943, the AAAAI has nearly 6,000
members in the United States, Canada and 60 other countries. The AAAAI serves
as an advocate to the public by providing educational information through its
Web site, www.aaaai.org , and its Physician Referral and Information Line, 1-800-822-2762.
Australian livestock industry continues to refine its traceability system. Meat
and Livestock Australia will continue to develop and improve the National Livestock
Identification System by providing database services, information and practical
field-based solutions. This was the commitment made by NLIS manager Mick Prendergast
to producers, who attended a series of NLIS meetings held across Queensland last
in Queensland sent a clear message that they have a number of technical issues
relating to the NLIS,¡± he said. ¡°We attended the meetings to listen to these concerns
and we are committed to following these issues up and where necessary delivering
He added: ¡°A
number of producers have come forward seeking help with the technology and I'd
like to encourage other producers to do the same. MLA has full confidence in the
NLIS. It is not a system that can be introduced overnight, but it is operating
successfully under Australian conditions and there are a range of solutions available.¡±
also committed to undertake a survey of current NLIS database users to clarify
and quantify any difficulties they may be having with the database. ¡°Conducting
a survey of users will give us hard evidence to act on,¡± he said.
will continue to develop demonstration sites and run information workshops to
help stakeholders better understand and get the most out of the NLIS. ¡°MLA, in
conjunction with state departments of agriculture have over 50 NLIS demonstration
sites around the country,¡± Prendergast emphasized. ¡°We are currently working with
the Queensland Department of Primary Industries to develop an additional 25 sites
in Queensland. We have delivered over 20 workshops around the country during the
past six months and the next series of workshops will begin at the end of March,
most of which will be held in Queensland.¡±
DETECTION OF ENTEROBACTER SAKAZAKII IN INFANT FORMULA
many readers will know, there is an increasing concern in the food industry about
the occurrence of Enterobacter sakazakii infections in neonates who have been
fed milk-based powdered infant formula. To assist food laboratories in the testing
of these products, we have introduced Oxoid Chromogenic Enterobacter sakazakii
Agar (Druggan-Forsythe-Iversen (DFI) formulation) that allows recovery and detection
of E. sakazakii in just 3 days - 2 days faster than by conventional methods. Enterobacter
sakazakii is a Gram-negative rod-shaped bacterium within the family Enterobacteriaceae.
The organism was called "yellow-pigmented Enterobacter cloacae" until
1980 when it was renamed Enterobacter sakazakii.1 Urmenyi and Franklin reported
the first two known cases of meningitis caused by E. sakazakii in 1961. Subsequently,
cases of meningitis, septicaemia, and necrotizing enterocolitis due to E. sakazakii
have been reported worldwide.
born prematurely and those with underlying medical conditions are at the highest
risk of developing E. sakazakii infection. Clusters of E. sakazakii infections
linked to powdered infant formula products from various manufacturers have been
reported in a number of countries. Outbreaks have also occurred in neonatal intensive
care units worldwide.2
2002 the FDA published a recommended method for isolating and identifying E. sakazakii
from infant formula: pre-enrichment in sterile water and enrichment in EE Broth
is followed by plating onto VRBG Agar then sub culture onto Tryptone Soya Agar.
Yellow-pigmented colonies are confirmed as E. sakazakii by oxidase and other biochemical
When compared to
the current FDA method, all clinical and food strains of E. sakazakii (95/95)
were detected on the new Oxoid chromogenic Enterobacter sakazakii Agar (DFI formulation)
two days sooner than the alternative method.3
and selective enrichment are followed by plating samples onto Oxoid Chromogenic
Enterobacter sakazakii Agar (DFI formulation). This innovative new chromogenic
medium contains the substrate 5-bromo-4-chloro-3-indolyl-¥á,D-glucopyranoside which
is cleaved by the enzyme ¥á-glucosidase, expressed by E. sakazakii, to form easily
distinguishable blue-green colonies.
Oxoid Chromogenic Enterobacter sakazakii
Agar (DFI Formulation) - CM1055
Lai KK. Enterobacter sakazakii infections among neonates, infants, children, and
adults. Medicine 2001;80:113-22.
van Acker et al. Outbreak of necrotizing enterocolitis associated with Enterobacter
sakazakii in powdered milk formula. J Clin Microbiol 2001;39:293-97
Data on file at Oxoid Ltd.
High Court lets Sizzler sue Excel over e.coli
on Tue, Mar. 23, 2004
U.S. Supreme Court let Worldwide Restaurant Concepts Inc.'s Sizzler USA sue a
meat company over an outbreak of E.coli poisoning that killed a girl who ate at
a Milwaukee Sizzler restaurant in 2000 and made others ill. The court refused
to hear an appeal by Excel Corp., a unit of Minnetonka-based Cargill Inc., seeking
to end the suit by Sizzler and some of those who became ill. Excel argued it couldn't
be sued in state court because the meat products it sold weren't considered "adulterated"
under federal standards. Sizzler plans to seek more than $10 million in damages
from Excel, a Sizzler lawyer said.
says 2004 advisory on mercury and fish consumption "should help targeted:
Populations understand the benefits of including fish in their diets"
National Food Processors Association ?Press Release
D.C.) - In response to the announcement by the Food and Drug Administration and
the Environmental Protection Agency of a 2004 advisory on methyl mercury and fish
consumption, targeted to pregnant women, women of childbearing age and young children,
Dr. Rhona Applebaum, Executive Vice President and Chief Science Officer of the
National Food Processors Association (NFPA), made the following comments:
2004 advisory underscores the importance of fish consumption, and should help
the targeted populations to better understand how a variety of fish - including
canned fish - can and should be included in healthful diets. The advisory states
that pregnant women, women of childbearing age and young children should not eat
Shark, Swordfish, Tilefish and King Mackerel and can safely eat up to 12 ounces
of a variety of fish each week, including canned light tuna, and up to six ounces
of canned albacore tuna a week, the latter translating to the equivalent of three
tuna sandwiches a week. "Fish consumption provides confirmed and real health
benefits, including, but not limited to, coronary heart benefits as well as benefits
to central nervous system development. Further, recent research has shown that
omega-3 fatty acids found in fish help lower the risk of heart disease. These
and other potential benefits would be lost if consumption of all fish were reduced.
It is critical that we provide information to consumers across the board that
helps them to understand how eating a variety of fish is essential to their health.
To repeat, the overwhelming health and nutritional benefits gained from fish consumption-to
all segments of the population-must continue to be explained to the public to
ensure that fish remains part of their diets and healthy lifestyles.
addition to FDA, a variety of other U.S. public health agencies and groups such
as the American Heart Association, the American College of Obstetrics and Gynecology,
and the American Academy of Pediatrics, have acknowledged the health and nutritional
benefits gained from fish consumption. Fish is an essential part of a healthful
diet for all consumers. Many scientific and medical studies have documented the
health benefits of fish, which are an excellent low-fat source of protein, vitamins,
minerals and other nutrients, including essential fatty acids.
be remembered that advisories such as this are guidance documents targeted at
select subsets of the population and do not represent the complete set of tools
for public health and nutrition education; they are not complete solutions in
and of themselves, nor should they be. We must be sure that these populations,
and consumers in general, do not interpret this 2004 advisory as a warning against
consuming all fish. More education efforts are needed to ensure that pregnant
women, women of childbearing age and the parents of young children understand
the importance of including a variety of fish in their diets and in the diets
of their families."
and EPA Announce the Revised Consumer Advisory on Methylmercury in Fish
for the 2004 FDA/EPA Consumer Advisory
FDA: What You Need to Know About Mercury
in Fish and Shellfish
EPA: What You Need to Know about Mercury in Fish and
Joint Federal Advisory for Mercury in Fish
Food Safety Regulatory
Essentials Training: Course Descriptions and Schedule page
of Remarks From Technical Briefing on BSE and Related Issues
and Trusted, Food Ingredients
Veneman Announces Expanded BSE Surveillance
Codex Alimentarius Commission: 32nd Session of the Codex Committee
on Food Labelling
Public Meeting to Address Codex Committee On Food Labeling
FSIS Constituent Update: March 12, 2004
How to Report Problems With Products
Regulated by FDA
Library of Export Requirements: Updated March 11, 2004
Commends Senate Passage of Bill Providing Improved Consumer Protection and Incentives
Guidebook for the Preparation of HACCP Plans and Generic HACCP Models
Guideline for Meat and Poultry Jerky
Allergenic Products Advisory Committee;
Notice of Meeting
U.S. Codex Office "What's New" Page: Updated March
Bovine spongiform encephalopathy; minimal risk regions and importation
Tummy bug takes hold [Australia]
03/19. Cholera claims 76 in Mozambique
Six hospitalised as bug strikes in the Waikato [NZ]
03/18. Source of school
outbreak might never be traced
03/18. Hash cake hospitalises teachers
Officials: Possible St. Louis school food-poisoning outbreak
03/17. Virus sickens
hotel's patrons in Las Vegas
03/17. Officials scrambling to determine what
sickened 45 students
03/17. Dozens Sick After St. Louis School Lunch
Students sickened at city school
03/16. Hepatitis A - Russia (Karachayevsk-Cherkessia)
03/16. Food poisoning, clostridial - Croatia (Zagreb)
gastroenteritis epidemic of 2002 associated with new n
03/15. West Coast oysters
responsible for food poisoning
03/12. Salmonella Outbreak Linked to L.A. Eatery
Fish, so foul! Foodborne illness caused by combined fish his
officials pin rash of illnesses on oysters
03/11. Six babies die in South Africa
after being fed with tainted
03/11. Kucinich released from hospital after being
treated for stom
03/11. Food Poisoning Traced to Deer-Soiled Lettuce
Listeriosis, neonatal - USA (CA)
03/10. 125 MP tribals fall ill after feast
03/09. Kucinich in Ohio Hospital with Stomach Flu
follows illness of two Marin infants
03/04. Pirates Notebook: Food poisons
03/03. 76 suffer food poisoning at wedding party in China
Invention could revolutionize decontamination & purification
working to hardwire cattle for health tracking
03/22. Industrial Vacuum Helps
Ensure Food Safety, Identified as th
03/22. Pathchek¢â Hygiene Monitoring Test
Now Available in Asia-Pacific Region
EXCLUSIVE: KSU working to hardwire cattle for health tracking
Daniel Yovich on 3/23/04 for Meatingplace.com
at Kansas State University are fine-tuning a system that could lay the groundwork
for a nationwide system to speedily track outbreaks of livestock diseases, an
innovation that could be of immeasurable assistance in the prevention of both
bio-terrorism induced illness and in containing outbreaks of naturally occurring
epidemics like foot-and-mouth disease.
maybe be three-to-five years before the KSU research is available to producers,
said Howard Erickson, a KSU professor of physiology and the current recipient
of the university's Roy W. Upham endowed chair. But within six to18 months, the
university is expected to field test in feed lots the high-tech system that will
monitor individual animal's breathing, heart rate, temperature and other health
indicators that could quickly pinpoint the source of an outbreak and raise the
alarm at the first sign of illness in a herd.
we're trying right now is to identify the parameters of what we need to track,"
Erickson told Meatingplace.com. "I think the push for this [research came
from Britain's] foot-and-mouth, but it clearly has applications as it applies
to bio-terrorism. And this doesn't have to be germane to just cattle. It can be
used with hogs or sheep."
KSU system uses wireless technology to monitor vital statistics, which can be
accessed by a ranch hand on a palm-held computer as the cattle approach feed and
watering sites. The technology also registers a history of when the 'wired' cattle
eat and drink, and the ultimate aim of the study is to come up with a prototype
that can form the backbone of a nationwide monitoring system very similar to those
being developed to detect human disease outbreaks.
current estimated cost to 'wire' an animal is about $100, but Erikson noted only
one or two animals in herd would need to be monitored to track outbreaks of infectious